"Creep"y and bearded Conan O'Brien rocks out during the writer's strike in this Youtube clip. He also screeches on the Beasties "Sabotage" in an extra special impersonation.
I knew Conan was an avid guitar player and remember hearing he knew he had made serious strides in his ax playing when he could recreate "The Wind Cries Mary" by Jimi Hendrix. I would just be happy with the "Come As You Are" riff, but to each his own. Rock on, Conan. Rock on.